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Peptide Building Blocks
AAT Bioquest offers a comprehensive selection of peptide building blocks for synthesizing fluorescent peptides, FRET-based probes, and bioconjugates. Our portfolio includes fluorescent amino acid derivatives and specialized linkers compatible with standard Fmoc solid-phase peptide synthesis protocols.
Our Peptide Technologies
Tide Quencher™ — Superior dark quenchers for FRET peptide substrates with minimal background
Tide Fluor™ — Bright, photostable fluorophores optimized for FRET donor applications
Tide Fluor™ — Bright, photostable fluorophores optimized for FRET donor applications
For custom services, please see here.
FMOC-Lys(Dye)
FMOC-lysine dye conjugates are pre-labeled building blocks for introducing fluorescent dyes, non-fluorescent quenchers, and haptens at lysine positions during solid-phase peptide synthesis.
- Tide Fluor™ and Tide Quencher™ labeled lysines
- Compatible with standard FMOC SPPS protocols
- Side-chain labeling preserves peptide backbone
- Multiple colors available for FRET pair design
- Applications in protease substrate synthesis
FMOC-Asp(Dye)
FMOC-aspartic acid dye conjugates enable side-chain labeling at aspartate positions in peptide synthesis.
- Fluorescent and quencher labels available
- Carboxylic acid side chain attachment
- Compatible with standard coupling conditions
- Useful for N-terminal positioned labels in FRET probes
FMOC-Glu(Dye)
FMOC-glutamic acid dye conjugates provide an alternative attachment point with longer side-chain spacer than aspartate.
- Extended linker reduces steric effects on dye fluorescence
- Tide Fluor™ and Tide Quencher™ options
- Suitable for FRET substrate design
- Compatible with automated peptide synthesizers
Special Amino Acids
Specialty amino acids include unnatural amino acids, monoprotected diamines that serve as versatile linkers in bioconjugate chemistry, and other modified building blocks for advanced peptide synthesis.
- Protected statine derivatives for synthesis of protease inhibitors
- Modified leucine analogs for creating novel peptides
- Monoprotected diamines as versatile bifunctional building blocks
This document (01.0326.251203r1) was last updated on Sat Feb 28 2026. All trademarks and registered trademarks mentioned herein are the property of their respective owners.
Peptide Building Blocks