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EDTA Azide
Product key features
- A unique EDTA building block
- Mild reaction conditions
- High reaction yield
Product description
EDTA azide is an excellent building block to develop site-specific ethylenediaminetetraacetic acid (EDTA) probes for variety of biomedical applications. It readily reacts with an alkyne compound (such as DBCO) under the well-known click chemistry conditions. EDTA is the most commonly used chelator for complexing transitional metal ions. EDTA chelation therapy uses the chelating agent, EDTA, to remove heavy metals and minerals from the body. It involves injecting EDTA into the bloodstream, where it binds to these substances, allowing them to be excreted through urine. EDTA is approved for treating lead poisoning, but it's also used in other conditions, including coronary artery disease and arthritis.
References
View all 25 references: Citation Explorer
Click Conjugates of Artificial Ribonucleases: Sequence Specific Cleavage with Multiple Turnover.
Authors: Weber, Sandra and Weinrich, Timo and Scheffer, Ute and Kalden, Elisabeth and Göbel, Michael W
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) (2025): e202500451
Authors: Weber, Sandra and Weinrich, Timo and Scheffer, Ute and Kalden, Elisabeth and Göbel, Michael W
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) (2025): e202500451
Decoration of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) with N-oxides increases the T1 relaxivity of Gd-complexes.
Authors: Kerpa, Svenja and Schulze, Verena R and Holzapfel, Malte and Cvancar, Lina and Fischer, Markus and Maison, Wolfgang
Journal: ChemistryOpen (2024): e202300298
Authors: Kerpa, Svenja and Schulze, Verena R and Holzapfel, Malte and Cvancar, Lina and Fischer, Markus and Maison, Wolfgang
Journal: ChemistryOpen (2024): e202300298
Exploring the Influence of Spacers in EDTA-β-Cyclodextrin Dendrimers: Physicochemical Properties and In Vitro Biological Behavior.
Authors: González-Méndez, Israel and Sorroza-Martínez, Kendra and González-Sánchez, Ignacio and Gracia-Mora, Jesús and Bernad-Bernad, María Josefa and Cerbón, Marco and Rivera, Ernesto and Yatsimirsky, Anatoly K
Journal: International journal of molecular sciences (2023)
Authors: González-Méndez, Israel and Sorroza-Martínez, Kendra and González-Sánchez, Ignacio and Gracia-Mora, Jesús and Bernad-Bernad, María Josefa and Cerbón, Marco and Rivera, Ernesto and Yatsimirsky, Anatoly K
Journal: International journal of molecular sciences (2023)
Synthesis of β-Cyclodextrin-Decorated Dendritic Compounds Based on EDTA Core: A New Class of PAMAM Dendrimer Analogs.
Authors: González-Méndez, Israel and Loera-Loera, Esteban and Sorroza-Martínez, Kendra and Vonlanthen, Mireille and Cuétara-Guadarrama, Fabián and Bernad-Bernad, María Josefa and Rivera, Ernesto and Gracia-Mora, Jesús
Journal: Pharmaceutics (2022)
Authors: González-Méndez, Israel and Loera-Loera, Esteban and Sorroza-Martínez, Kendra and Vonlanthen, Mireille and Cuétara-Guadarrama, Fabián and Bernad-Bernad, María Josefa and Rivera, Ernesto and Gracia-Mora, Jesús
Journal: Pharmaceutics (2022)
Click chemistry inspired synthesis of andrographolide triazolyl conjugates for effective fluorescent sensing of ferric ions.
Authors: Pandey, Nishant and Jyoti, and Singh, Mangat and Dwivedi, Pratibha and Sahoo, Subash C and Mishra, Bhuwan B
Journal: Natural product research (2022): 5438-5448
Authors: Pandey, Nishant and Jyoti, and Singh, Mangat and Dwivedi, Pratibha and Sahoo, Subash C and Mishra, Bhuwan B
Journal: Natural product research (2022): 5438-5448
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