Rhod-4™ maleimide
Rhod-4™ maleimide is an excellent building block that can be readily used to prepare a calcium-sensitive bioconjugate for monitoring calcium change spatially for a specific target. It can be selectively conjugated to thiol-containing biomolecules such as antibodies, thiol-modified oligos, or peptides containing a cysteine residue. Rhod-4™ is a fluorescent calcium indicator dye commonly used in cell biology and neuroscience research. It belongs to the family of rhodol-based calcium. Rhod-4™ is a high-affinity calcium indicator dye that exhibits changes in fluorescence intensity upon binding to calcium ions. When Rhod-4™ binds to calcium, its fluorescence intensity increases dramatically, allowing researchers to measure and monitor changes in calcium levels. Compared to the traditional Rhod-2, Rhod-4™ is a superior replacement. It is a valuable tool in calcium imaging research, enabling the detection and quantification of intracellular calcium dynamics. It's fluorescence properties and calcium binding specificity make it suitable for studying calcium signaling in various cell types and biological systems.
Spectrum
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Product family
Name | Excitation (nm) | Emission (nm) | Quantum yield |
Rhod-4™, AM | 523 | 551 | 0.11 |
References
View all 50 references: Citation Explorer
Mitochondria-Endoplasmic Reticulum Contact Sites Dynamics and Calcium Homeostasis Are Differentially Disrupted in PINK1-PD or PRKN-PD Neurons.
Authors: Grossmann, Dajana and Malburg, Nina and Glaß, Hannes and Weeren, Veronika and Sondermann, Verena and Pfeiffer, Julia F and Petters, Janine and Lukas, Jan and Seibler, Philip and Klein, Christine and Grünewald, Anne and Hermann, Andreas
Journal: Movement disorders : official journal of the Movement Disorder Society (2023)
Authors: Grossmann, Dajana and Malburg, Nina and Glaß, Hannes and Weeren, Veronika and Sondermann, Verena and Pfeiffer, Julia F and Petters, Janine and Lukas, Jan and Seibler, Philip and Klein, Christine and Grünewald, Anne and Hermann, Andreas
Journal: Movement disorders : official journal of the Movement Disorder Society (2023)
Cardiomyocyte Targeting Peptide to Deliver Amiodarone.
Authors: Zahid, Maliha and Weber, Beth and Yurko, Ray and Islam, Kazi and Agrawal, Vaishavi and Lopuszynski, Jack and Yagi, Hisato and Salama, Guy
Journal: bioRxiv : the preprint server for biology (2023)
Authors: Zahid, Maliha and Weber, Beth and Yurko, Ray and Islam, Kazi and Agrawal, Vaishavi and Lopuszynski, Jack and Yagi, Hisato and Salama, Guy
Journal: bioRxiv : the preprint server for biology (2023)
The Effect of Primary Root Canal Treatment on Dentinal Tubule Penetration of Calcium Silicate-based Sealers during Endodontic Retreatment.
Authors: Eğemen, Ayşenur and Belli, Sema
Journal: Journal of endodontics (2022): 1169-1177
Authors: Eğemen, Ayşenur and Belli, Sema
Journal: Journal of endodontics (2022): 1169-1177
Dual SGLT-1 and SGLT-2 inhibition improves left atrial dysfunction in HFpEF.
Authors: Bode, David and Semmler, Lukas and Wakula, Paulina and Hegemann, Niklas and Primessnig, Uwe and Beindorff, Nicola and Powell, David and Dahmen, Raphael and Ruetten, Hartmut and Oeing, Christian and Alogna, Alessio and Messroghli, Daniel and Pieske, Burkert M and Heinzel, Frank R and Hohendanner, Felix
Journal: Cardiovascular diabetology (2021): 7
Authors: Bode, David and Semmler, Lukas and Wakula, Paulina and Hegemann, Niklas and Primessnig, Uwe and Beindorff, Nicola and Powell, David and Dahmen, Raphael and Ruetten, Hartmut and Oeing, Christian and Alogna, Alessio and Messroghli, Daniel and Pieske, Burkert M and Heinzel, Frank R and Hohendanner, Felix
Journal: Cardiovascular diabetology (2021): 7
Whole brain irradiation in mice causes long-term impairment in astrocytic calcium signaling but preserves astrocyte-astrocyte coupling.
Authors: Institoris, Adam and Murphy-Royal, Ciaran and Tarantini, Stefano and Yabluchanskiy, Andriy and Haidey, Jordan N and Csiszar, Anna and Ungvari, Zoltan and Gordon, Grant R
Journal: GeroScience (2021): 197-212
Authors: Institoris, Adam and Murphy-Royal, Ciaran and Tarantini, Stefano and Yabluchanskiy, Andriy and Haidey, Jordan N and Csiszar, Anna and Ungvari, Zoltan and Gordon, Grant R
Journal: GeroScience (2021): 197-212
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