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TRITC–dextran conjugate (average MW = ~20K)

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ShippingStandard overnight for United States, inquire for international
Physical properties
Molecular weight~21000
Spectral properties
Correction Factor (260 nm)0.27
Correction Factor (280 nm)0.34
Extinction coefficient (cm -1 M -1)100000
Excitation (nm)544
Emission (nm)570
Storage, safety and handling
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure


Molecular weight
Correction Factor (260 nm)
Correction Factor (280 nm)
Extinction coefficient (cm -1 M -1)
Excitation (nm)
Emission (nm)
TRITC-labeled dextran is used in cardiovascular, microcirculation, perfusion, cell monolayer and cell membrane permeability research as fluorescent flux tracer compound that supports the measurement of processes such as blood flow, membrane damage, vascular drainage and renal elimination. It is also used in microcirculation and cell permeability research utilizing microfluorimetry, and possible in perfusion studies in animals. TRITC-dextran has also been used to study plant cell wall porosity and capillary permeability. Plasma proteins have been shown not to bind to TRITC-dextran. Small TRITC-dextrans are often used to measure processes such as endocytosis and cell junction permeability. Rhodamine-dextran, 20 kDa, may be used to study cell processes (such as endocytosis and osmoporation), endothelial or epithelial monolayer porosity, apical-basolateral movements within cell layers and cell junction permeability and drug release from structures such as hydrogens and collagen minirods.


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Spectral properties

Correction Factor (260 nm)0.27
Correction Factor (280 nm)0.34
Extinction coefficient (cm -1 M -1)100000
Excitation (nm)544
Emission (nm)570

Product Family

NameExcitation (nm)Emission (nm)Extinction coefficient (cm -1 M -1)Correction Factor (280 nm)Correction Factor (260 nm)
FITC–dextran conjugate (average MW = ~20K)491516730000.35-
TRITC–dextran conjugate (average MW = ~70K)5445701000000.340.27
TRITC–dextran conjugate (average MW = ~150K)5445701000000.340.27



View all 7 citations: Citation Explorer
SIRB, sans iron oxide rhodamine B, a novel cross-linked dextran nanoparticle, labels human neuroprogenitor and SH-SY5Y neuroblastoma cells and serves as a USPIO cell labeling control
Authors: Shen, W. B., Vaccaro, D. E., Fishman, P. S., Groman, E. V., Yarowsky, P.
Journal: Contrast Media Mol Imaging (2016): 222-8
In vivo retrograde labeling of neurons in the zebrafish embryo or larva with rhodamine dextran
Authors: Volkmann, K., Koster, R. W.
Journal: CSH Protoc (2007): pdb prot4832
Tracing of axonal connectivities in a combined slice preparation of rat brains--a study by rhodamine-dextran-amine-application in the lateral nucleus of the amygdala
Authors: von Bohlen und Halbach, O., Albrecht, D.
Journal: J Neurosci Methods (1998): 169-75
Multiple anterograde tracing, combining Phaseolus vulgaris leucoagglutinin with rhodamine- and biotin-conjugated dextran amine
Authors: Dolleman-Van der Weel, M. J., Wouterlood, F. G., Witter, M. P.
Journal: J Neurosci Methods (1994): 9-21
Tracing of axonal connections by rhodamine-dextran-amine in the rat hippocampal-entorhinal cortex slice preparation
Authors: Boulton, C. L., von Haebler, D., Heinemann, U.
Journal: Hippocampus (1992): 99-106
Labeling of developing vascular endothelium after injections of rhodamine-dextran into blastomeres of Xenopus laevis
Authors: Rovainen, C. M.
Journal: J Exp Zool (1991): 209-21
In vivo anterograde and retrograde axonal transport of the fluorescent rhodamine-dextran-amine, Fluoro-Ruby, within the CNS
Authors: Schmued, L., Kyriakidis, K., Heimer, L.
Journal: Brain Res (1990): 127-34