How do mitochondria produce reactive oxygen species?
Posted April 2, 2020
Mitochondria produce reactive oxygen species (ROS) as by-products during oxidative phosphorylation. Since oxygen readily accepts free electrons, ROS such as O2- (superoxide), as well as H2O2 (hydrogen peroxide) and .OH (hydroxyl radical), are easily formed.
Overproduction of reactive oxygen species can lead to oxidative stress and result in damage of protein, lipids, and DNA.
MitoROS™ 580 *Optimized for Detecting Reactive Oxygen Species (ROS) in Mitochondria*
Cell Meter™ Fluorimetric Mitochondrial Superoxide Activity Assay Kit *Green Fluorescence*
Cell Meter™ Intracellular Colorimetric Lipid Peroxidation (MDA) Assay Kit