What is RNA splicing?

Posted June 22, 2020

Answer

RNA splicing is a form of RNA processing for the maturation of mRNA. During splicing, introns in the precursor messenger RNA (pre-mRNA) are removed and exons are joined, leading to the formation of a mature messenger RNA (mRNA). Several methods of RNA splicing exist in nature, for example, self-splicing, tRNA splicing and splicing by spliceosome. The type of splicing depends on the organism, structure of intron, and the requirement of catalysts.

Additional resources

6-ROX glycine *25 uM fluorescence reference solution for PCR reactions*

Perdew, G. H., Heuvel, J. P. V., & Peters, J. M. (2008). Regulation of gene expression. Springer Science & Business Media.

Lodish, H., Berk, A., Kaiser, C. A., Krieger, M., Scott, M. P., Bretscher, A., ... & Matsudaira, P. (2008). Molecular cell biology. Macmillan.