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AAT Bioquest

What is the difference between next-generation (NGS) and high-throughput sequencing (HTS)?

Posted May 9, 2020


Answer

Next-generation sequencing is another term that is used for high-throughput sequencing, which involves processing a large number of DNA fragments in parallel. These terms encompass both second generation sequencing, which works with short read lengths, and third generation sequencing, which can work with longer read lengths.

Additional resources

Ambardar, S., Gupta, R., Trakroo, D., Lal, R., & Vakhlu, J. (2016). High throughput sequencing: an overview of sequencing chemistry. Indian journal of microbiology, 56(4), 394-404.