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AAT Bioquest

Is next-generation sequencing (NGS) better than Sanger sequencing?

Posted May 9, 2020


Answer

While next-generation sequencing is faster and much more cost effective when sequencing a high number of gene targets or a whole genome, Sanger sequencing is still more cost for sequencing smaller numbers of targets or samples. In addition, Sanger sequencing is also useful for validating NGS results due to its high accuracy.

Additional resources

MagaDye™ 4 Color Sanger Sequencing Terminator Kit

Discovering viral genome by Sanger Sequencing