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AAT Bioquest

What is the mitosis phase in a cell cycle and what are the phases of mitosis phase?

Posted June 1, 2020


Answer

Mitosis phase is a short period of cell cycle when chromosome is separated to facilitate a complete cell division. There are mainly 4 phases in mitosis phase:

 

  • Prophase: Chromatin condenses into chromosomes and nuclear envelope disappears.
  • Metaphase: The pairs of condensed chromosomes line up along the equator of the elongated cell.
  • Anaphase: The sister chromatids are drawn to opposite poles (ends) of the elongated cell and the chromosomes are split apart.
  • Telophase: The chromosomes are at the poles and are becoming more diffuse. The nuclear envelope is reforming, and the cytoplasm may be dividing.

 

After telophase, the genetic contents of one cell have been divided equally into two cells. However, cell division is not complete until cytokinesis takes place, which is not a phase of mitosis but necessary for completing cell division. Cytokinesis starts before anaphase ends and completes shortly after telophase, which divides the cell’s cytoplasm and results in irreversible separation leading to two daughter cells.

Additional resources

ReadiUse™ CFSE [5-(and 6)-Carboxyfluorescein diacetate, succinimidyl ester] *CAS 150347-59-4*

Bucculite™ FdU Cu-Free Cell Proliferation Fluorescence Imaging Kit *Deep Red Fluorescence*

Morgan, D. O. (2007). The cell cycle: principles of control. New Science Press.