AAT Bioquest

What is the purpose of DNA fragmentation?

Posted February 17, 2022


DNA fragmentation subdivides longer DNA strands into smaller fragments prior to sequencing. This is essential as sequencing provides most accurate results when performed on relatively short strands of 100-500 base pairs. DNA fragmentation plays an integral role in forensics, particularly that of DNA profiling.

Additional resources

Measuring Sperm DNA Fragmentation and Clinical Outcomes of Medically Assisted Reproduction: A Systematic Review and Meta-Analysis

Cell Meter™ Live Cell TUNEL Apoptosis Assay Kit *Red Fluorescence*