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AAT Bioquest

What kinds of reactions do transferases catalyze?

Posted September 7, 2021


Answer

Transferases catalyze the transfer of functional groups such as alkyl, methyl, acyl, carbonyl, hydroxymethyl, phosphoryl, glycosyl, carboxyl, and sulfate, from a donor molecule to an acceptor molecule. Transferases are involved in numerous biochemical reactions in the cell.

For example, during translation, the peptidyl transferase catalyzes the transfer of an amino acid chain, which is a functional group, from the tRNA molecule in the A-site of the ribosome to the tRNA in the P-site

Additional resources

Strategies for the Expression and Characterization of Artificial Myoglobin-based Carbene Transferases

Amplite® Colorimetric Aspartate Aminotransferase (AST) Assay Kit