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Why is serum used in cell culture?
Posted July 22, 2020
Cell CultureEnzymeslipid
Answer

Serum has been widely used as a supplement for the in vitro cell culture. It is an important source for growth and adhesion factors, hormones, lipids and mineral. Besides, it participates in the regulation of cell membrane permeability, and can serve as a carrier for lipids, enzymes, micronutrients, and trace elements into the cell.

Additional resources
Assay development services Freshney, R. I. (2005). Serum?Free Media. Culture of animal cells: a manual of basic technique. van der Valk, J., Bieback, K., Buta, C., Cochrane, B., Dirks, W., Fu, J., ... & Pistollato, F. (2018). Fetal bovine serum (FBS): past–present–future. Altex, 35(1), 1-20.

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