Are any bases methylated by default? | AAT Bioquest

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Are any bases methylated by default?

Posted January 3, 2024

Cell Signaling Cellular Processes DNA and RNA Quantitation Gene Expression Analysis & Genotyping Nucleic Acids Nucleus

Answer

Cytosine bases of eukaryotic DNA are most commonly associated with DNA methylation. Cytosine bases are converted to 5-methylcytosine by DNA methyltransferase (DNMT) enzymes. Cytosine methylation is common in both eukaryotes and prokaryotes. However, the rate of DNA methylation varies considerably from one species to another.

Additional resources

Cytosine methylation and DNA repair DNA Methylation Helixyte™ Green ssDNA reagent

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