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AAT Bioquest

Are cytotoxic T-cells in innate immunity?

Posted August 24, 2023


Answer

No. Cytotoxic T-cells are involved in cell-mediated immunity, a type of adaptive immunity. 

The immune system is divided into innate and adaptive components, each of which has a distinct role and function. Innate immunity is present in the body at all times. Natural killer cells that are a part of innate immunity don’t need activation to attack harmful cells. On the other hand, adaptive immunity is triggered on encountering a foreign pathogen. Cytotoxic T cells, which are part of the adaptive immune response, only attack viruses when activated by an antigen. They play a pivotal role in immune defense against intracellular pathogens such as bacteria and viruses and against tumors.

Additional resources

The T cell as a bridge between innate and adaptive immune systems: implications for the kidney

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