AAT Bioquest

Are peptidases enzymes?

Posted May 19, 2023


Yes, peptidases are enzymes. Peptidases are a type of proteolytic enzyme that cleave peptide bonds in proteins by hydrolysis, breaking down the long chainlike protein molecules into shorter fragments or peptides, which are then further broken down into their components, amino acids

Peptidase enzymes are broken down into two categories - endopeptidases and exopeptidases - according to the location of the peptide bond cleavage. Endopeptidases cleave internal peptide bonds, while exopeptidases cleave the terminal peptide bonds in a peptide chain. 

Additional resources

Peptidases: structure, function and modulation of peptide‐mediated effects in the human lung


Amplite® Universal Fluorimetric Protease Activity Assay Kit *Green Fluorescence*