AAT Bioquest

How many ATP molecules can be generated from fatty acid oxidation?

Posted July 19, 2022


More than one hundred ATP molecules can be generated from the complete oxidation of one molecule of fatty acid. The exact number of ATP molecules generated depends on the number of carbon atoms in the fatty acid that is being oxidized. For example, palmitic acid, which is the most common type of fatty acid, contains 16 carbon atoms and no carbon-carbon double bonds. Complete oxidation of one palmitate molecule containing 16 carbons generates 129 ATP molecules.

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