AAT Bioquest

Is ATP hydrolysis exergonic?

Posted May 9, 2023


Yes, ATP hydrolysis is exergonic as it yields energy. 

ATP has three phosphate groups linked to each other by high-energy bonds. During ATP hydrolysis, a phosphate group is broken off the tail of an ATP molecule and the energy in the bond is released. Reactions that produce energy are referred to as exergonic reactions.

Additional resources

The Complex Roles of Adenosine Triphosphate in Bioenergetics

PhosphoWorks™ Luminometric ATP Assay Kit *DTT-Free*

PhosphoWorks™ Fluorimetric ADP Assay Kit *Red Fluorescence*