AAT Bioquest

In what phase does chromatin coil and condense, forming chromosomes?

Posted July 28, 2023


During prophase, the chromatin coils and condenses to become progressively compact, resulting in the production of visible chromosomes. During this stage of the cell cycle, the chromosomes become distinguishable under a microscope. The condensation of chromatin into visible chromosomes during mitosis allows for the proper segregation and distribution of genetic material into daughter cells. This process can also be described as DNA supercoiling, as it changes from chromatin to distinct chromosomes. 

Additional resources

Genetics, Meiosis

Cell Cycle Assays

Helixyte™ Green ssDNA reagent

Hoechst 33258 *CAS 23491-45-4*

Chromatin Immunoprecipitation (ChIP)