Basis of differentiation | Chromatin | Chromatids |
Definition | Chromatin is the readily stainable substance of a cell nucleus, consisting of DNA, RNA, and various proteins that form chromosomes during cell division | A chromatid is one of two genetically identical chromosome strands in which a chromosome splits longitudinally to prepare for cell division |
Composition | Chromatin consists of DNA molecules wrapped around histone proteins, forming nucleosomes | Chromatids are replicated copies of a single chromosome that join together at the centrosome |
Presence in cell cycle | Chromatin is present throughout the entire cell cycle, and uncoil to become less condensed following telophase | Chromatids are only present during the late stages of the cell cycle; they begin separating during metaphase and are at opposite poles of the cell during anaphase |
Function | Chromatin acts the template for gene expression and allows for the proper packaging and organization of DNA (wrapped around histones) | Chromatids primarily function in the distribution of genetic material during cell division |
Structure | When not dividing, chromatin exists as a filamentos and loose structure in the nucleus | Chromatids consists of one DNA molecule that is tightly coiled and condensed |