It has been determined by various agencies such as OSHA, the European Food Safety Authority, and the IARC that coumarin is not carcinogenic to humans. There was originally some speculation in 2004 that genotoxicity was possible in humans, but that was proved to be false by the European Food Safety Authority. Humans can safely eat food with coumarin (although not in high concentrations), as well as use cosmetic and tobacco products containing the substance.