AAT Bioquest

Are coumarins water-soluble?

Posted October 14, 2022


Coumarin is slightly soluble in water, however it is more soluble in hot water compared to cold water. Coumarin is in fact 8 times more soluble in hot water than in cold water. In addition, coumarin is also highly soluble in ethanol, chloroform, and ether. 

Additional resources


AMCA Alkyne

Amplite® Ethanol Quantitation Kit

Solubility of coumarin in (ethanol + water) mixtures: Determination, correlation, thermodynamics and preferential solvation