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Are coumarins water-soluble?

Posted October 14, 2022


Chemical Reagents
Bioconjugation
Classic Dyes
Coumarins
Answer

Coumarin is slightly soluble in water, however it is more soluble in hot water compared to cold water. Coumarin is in fact 8 times more soluble in hot water than in cold water. In addition, coumarin is also highly soluble in ethanol, chloroform, and ether. 

Additional resources

Coumarins

AMCA Alkyne

Amplite® Ethanol Quantitation Kit

Solubility of coumarin in (ethanol + water) mixtures: Determination, correlation, thermodynamics and preferential solvation

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