Is MTT cell permeable?

Posted October 26, 2022

Bioconjugation Cell Cycle Assays Cell Proliferation Assays Cell Structures and Organelles Cell Viability Assays Cellular Processes

Answer

Yes, methylthiazolydipheny-tetrazolium bromide (MTT) has strong membrane permeability. MTT produces a yellowish tetrazole solution that is converted to purple, water-insoluble MTT formazan crystals by NADPH-oxidoreductases.

Additional resources

Cell Meter™ Colorimetric MTT Cell Proliferation Kit Cell Viability Assays Cell Meter™ Colorimetric WST-8 Cell Quantification Kit A study of some variables in a tetrazolium dye (MTT) based assay for cell growth and chemosensitivity

Why is DMSO added in MTT assay?What are the basic phases of mitosis?What are the common methods used to measure cell proliferation?How are epithelial tissues classified?What is flow cytometry used for?

Related questions