What are the advantages of targeted resequencing?

Targeted resequencing allows researchers to concentrate their efforts and resources on specific target areas, making it more efficient and cost-effective. Targeted sequencing generates datasets that are substantially smaller than those produced by WGS, as only the specified genomic regions are sequenced.

Thus, researchers can achieve higher coverage depths, increasing the likelihood of detecting low-frequency variants that may be missed in whole-genome sequencing (WGS) studies. Additionally, targeted sequencing is highly scalable and adaptable to varying sample sizes and sequencing throughput requirements.