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AAT Bioquest

What are the characteristics of lyases?

Posted March 26, 2024


Answer

Key Characteristics of Lyases:

  • Lyases catalyze reactions in which chemical groups are either added to a substrate or removed from it, resulting in the creation of new bonds and alterations in the structure of the molecule. 
  • Lyases play crucial roles in various metabolic pathways including the tricarboxylic acid (TCA) cycle, contributing to processes essential for intermediary metabolism and energy production. 
  • Many lyases catalyze condensation or dehydration reactions in which they eliminate water molecules while breaking or forming breaking chemical bonds.
  • Lyases function independently of water molecules, unlike hydrolases, which depend on the presence of water in their catalytic process.
  • Lyases may utilize coenzymes such as pyridoxal phosphate to aid in their catalytic functions.
Additional resources

CS Lyases: Structure, Activity, and Applications in Analysis and the Treatment of Diseases

Enzymes

Peptide and Protein Molecular Weight Calculator