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AAT Bioquest

What are the differences between active transport and facilitated diffusion?

Posted November 21, 2023


Answer

Basis of differentiation

Active transport

Facilitated diffusion

Definition

The movement of ions or molecules across cell membranes into a region of higher concentration (against the gradient) and is assisted by enzymes

Is the transport of substances across a membrane from a region of higher concentration to lower concentration by carrier or channel proteins

Energy requirement

Requires energy to move molecules against their concentration gradient

Does not use energy

Process

Is active, and occurs against the concentration gradient 

Is passive and occurs along the concentration gradient

End mechanism

Causes the accumulation molecules such as glucose and amino acids, active transport does not stop

Facilitated diffusion stops when equilibrium is released 

Proteins

Sodium-potassium pump, ATPases, sodium/glucose symporter

Gated ion channels

Additional resources

Physiology, Active Transport

Plasma Membrane

Cell Navigator® Cell Plasma Membrane Staining Kit *Green Fluorescence*