What are the differences between Isoschizomers and Neoschizomers?
Posted April 4, 2024
Answer
Isoschizomers
- Isoschizomers are restriction enzymes that have the same recognition sequence and cleave the DNA at the same positions.
- They have the same specificities and their formation is interchangeable
- They generate the same types of ends
- Examples include: Hpall and MSPI, Agel and BshT1, Kpn1 and Acc651
Neoschizomers
- Neoschizomers are restriction enzymes that have the same recognition sequence but cleave DNA at different positions
- They have different specificities and their formation is rigid and not interchangeable
- They generate different types of ends
- Examples include: Maell and Tail, Smal and Xmal, Apal and Bsp120l
Additional resources
Restriction Enzymes Cut Sites Reference Table
Amplite® Fluorimetric Coenzyme A Quantitation Kit *Green Fluorescence*