What are the differences between protease and peptidase?
Posted May 19, 2023
- Protease is a type of hydrolytic enzyme that breaks down proteins by cleaving the peptide bond in protein molecules. They have an affinity for intact proteins.
- Proteases can be either endopeptidases or exopeptidases. Endopeptidases hydrolyze internal peptide bonds, resulting in oligopeptides.
- Common examples of endopeptidases include trypsin, papain, pepsin, elastase, and chymotrypsin.
- Peptidase is a type of protease enzyme that breaks down peptides into amino acids by cleaving the end terminals of the peptide chain. They have an affinity for small peptides.
- Peptidases are only exopeptidases. They hydrolyze peptide bonds at the ends of the peptide chain, resulting in a single amino acid or dipeptide.
- Common examples of peptidases include carboxypeptidase A and aminopeptidases.