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AAT Bioquest

What are the examples of energy coupling that use ATP hydrolysis?

Posted March 30, 2023


Answer

There are several examples of energy coupling mechanisms that use ATP hydrolysis. One type is ATP hydrolysis coupled with glucose to glucose-6-phosphate conversion. The enzyme hexokinase catalyzes the conversion of glucose to glucose-6-phosphate. This is an irreversible reaction and requires ATP. It is also a part of glycolysis. ATP hydrolysis is also coupled with the sodium and potassium pumps. This process moves sodium and potassium ions across the cell membrane through energy from ATP hydrolysis. It uses the enzyme Na+/K+-ATPase. ATP hydrolysis can also be coupled with starch/glycogen/cellulose formation. The enzyme starch synthase holds the glucose phosphate molecules together by utilizing the energy produced by ATP. 

Additional resources

Pathway of processive ATP hydrolysis by kinesin

Cellular Processes

PhosphoWorks™ Luminometric ATP Assay Kit *DTT-Free*

Cell Meter™ Live Cell ATP Assay Kit