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What are the principles of simple staining?
Posted August 15, 2024

Answer

In simple staining, a single dye is used to color the bacterial smear, creating a clear contrast between the bacteria and the background. Basic stains, which have a positive charge, are often used because the negative charges on bacterial nucleic acids and some cell wall parts attract and bind these positively charged dyes. The main goal of simple staining is to reveal the shape and arrangement of bacterial cells.