AAT Bioquest

What are the similarities between reversible and irreversible cell injury?

Posted January 26, 2023


There are several similarities between reversible and irreversible cell injury. One similarity is that both types of cell injuries occur as a result of an external chemical, biological, or physical agent; the cells affected by both types of cell injury have their regular homeostasis disturbed. Both types of cell injury also induce some type of stress to the cells. Additionally, both types of injuries can also lead to cell death, once an injury proceeds from reversible to irreversible. Both types of injuries also elicit a specific, and abnormal cellular response. Lastly, in both types of injuries, internal intracellular mechanisms are occurring. For example, it may be blebbing in reversible cell injury, or Cytochrome C leakage that generates cell death in irreversible cell injury.

Additional resources

Histology, Cell Death

Cell Meter™ Intracellular NADH/NADPH Flow Cytometric Analysis Kit *Red Fluorescence*

PhosphoWorks™ Colorimetric ATP Assay Kit