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What are the two groups of AChE inhibitors?
Posted March 27, 2024
BioconjugationCellular ProcessesCellular Structures and OrganellesEnzymes
Answer

AChE (Acetylcholinesterase) inhibitors prevent the enzyme acetylcholinesterase from breaking down the neurotransmitter acetylcholine (ACh), extending the during of its action. 

Based on the mode of action, AChE inhibitors can be divided into two groups: 

  1. Reversible AChE inhibitors
  2. Irreversible AChE inhibitors.
Additional resources
Acetylcholinesterase Inhibitors: Pharmacology and Toxicology EnzymesAmplite® Colorimetric Acetylcholinesterase Assay Kit

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