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AAT Bioquest

What is the end product of transcription?

Posted March 1, 2023


Answer

The end product of transcription is an RNA transcript. This could be any form of RNA such as mRNA (messenger RNA), rRNA (ribosomal RNA), tRNA (transfer RNA), or non-coding RNA. Prokaryotes form a polycistronic mRNA whereas eukaryotes form a monocistronic mRNA. Transcription is catalyzed by the enzyme RNA polymerase. In prokaryotes, all three types of RNA are produced by a single RNA polymerase. In eukaryotes, transcription is catalyzed by three different types of RNA polymerase and each one forms a different type of RNA: 

  1. RNA polymerase 1 produces rRNA, a component of a ribosome that facilitates translation 
  2. RNA polymerase 2 produces mRNA, which is responsible for carrying genetic information from the nucleus to the cytoplasm
  3. RNA polymerase 3 produces tRNA, which carries the corresponding amino acid to the ribosomes during translation
Additional resources

Modulation of mRNA 3'-End Processing and Transcription Termination in Virus-Infected Cells

DNA and RNA Quantitation

Portelite™ Fluorimetric RNA Quantitation Kit*Optimized for Cytocite™ and Qubit™ Fluorometers*