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What is viability PCR (vPCR)?

Posted July 17, 2024


Chemical Reagents
Cell Viability Assays
Cellular Structures and Organelles
Physiological Probes
Plasma Membrane
Polymerase Chain Reaction (PCR)
Answer

Viability PCR (vPCR) is an advanced version of PCR that allows for the detection of only live cells by neutralizing the DNA of dead cells through a pre-treatment process using specific intercalating photo-reactive reagents.  

Additional resources

Use of viability PCR for detection of live Chlamydia trachomatis in clinical specimens

Cell Viability Assays

Calcein, AM *UltraPure grade* *CAS 148504-34-1*

Polymerase Chain Reaction (PCR)

Related questions
How does viability PCR (vPCR) work?
What are the commonly used viability PCR reagents?
What is Propidium Monoazide (PMA)?
What are the applications of viability PCR (vPCr)?
What are the factors that might cause the overestimation of live cells in PMA-treated samples?