Z-DEVD-FMK
Ordering information
Price | |
Catalog Number | |
Unit Size | |
Quantity |
Additional ordering information
Telephone | 1-800-990-8053 |
Fax | 1-800-609-2943 |
sales@aatbio.com | |
International | See distributors |
Bulk request | Inquire |
Custom size | Inquire |
Shipping | Standard overnight for United States, inquire for international |
Physical properties
Molecular weight | 668.67 |
Solvent | DMSO |
Storage, safety and handling
H-phrase | H303, H313, H333 |
Hazard symbol | XN |
Intended use | Research Use Only (RUO) |
R-phrase | R20, R21, R22 |
Storage | Freeze (< -15 °C); Minimize light exposure |
UNSPSC | 12171501 |
Calculators
Common stock solution preparation
Table 1. Volume of DMSO needed to reconstitute specific mass of Z-DEVD-FMK to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.
0.1 mg | 0.5 mg | 1 mg | 5 mg | 10 mg | |
1 mM | 149.551 µL | 747.753 µL | 1.496 mL | 7.478 mL | 14.955 mL |
5 mM | 29.91 µL | 149.551 µL | 299.101 µL | 1.496 mL | 2.991 mL |
10 mM | 14.955 µL | 74.775 µL | 149.551 µL | 747.753 µL | 1.496 mL |
Molarity calculator
Enter any two values (mass, volume, concentration) to calculate the third.
Mass (Calculate) | Molecular weight | Volume (Calculate) | Concentration (Calculate) | Moles | ||||
/ | = | x | = |
Product Family
Name | Excitation (nm) | Emission (nm) |
Z-DEVD-AFC | 376 | 482 |
Z-DEVD-AMC | 341 | 441 |
TF3-DEVD-FMK | 554 | 578 |
Z-DEVD-aminoluciferin | 362 | 499 |
References
View all 50 references: Citation Explorer
Rescue of Escherichia coli cells from UV-induced death and filamentation by caspase-3 inhibitor.
Authors: Wadhawan, Surbhi and Gautam, Satyendra
Journal: International microbiology : the official journal of the Spanish Society for Microbiology (2019): 369-376
Authors: Wadhawan, Surbhi and Gautam, Satyendra
Journal: International microbiology : the official journal of the Spanish Society for Microbiology (2019): 369-376
AGEs Induce Apoptosis in Rat Osteoblast Cells by Activating the Caspase-3 Signaling Pathway Under a High-Glucose Environment In Vitro.
Authors: Liu, Jiaqiang and Mao, Jing and Jiang, Yi and Xia, Lunguo and Mao, Lixia and Wu, Yong and Ma, Pan and Fang, Bing
Journal: Applied biochemistry and biotechnology (2016): 1015-27
Authors: Liu, Jiaqiang and Mao, Jing and Jiang, Yi and Xia, Lunguo and Mao, Lixia and Wu, Yong and Ma, Pan and Fang, Bing
Journal: Applied biochemistry and biotechnology (2016): 1015-27
Cleavage of the calpain inhibitor, calpastatin, during postmortem ageing of beef skeletal muscle.
Authors: Huang, Feng and Huang, Ming and Zhang, Hong and Guo, Bing and Zhang, Dequan and Zhou, Guanghong
Journal: Food chemistry (2014): 1-6
Authors: Huang, Feng and Huang, Ming and Zhang, Hong and Guo, Bing and Zhang, Dequan and Zhou, Guanghong
Journal: Food chemistry (2014): 1-6
Increased activity of cell surface peptidases in HeLa cells undergoing UV-induced apoptosis is not mediated by caspase 3.
Authors: Piva, Terrence J and Davern, Catherine M and Hall, Paula M and Winterford, Clay M and Ellem, Kay A O
Journal: International journal of molecular sciences (2012): 2650-75
Authors: Piva, Terrence J and Davern, Catherine M and Hall, Paula M and Winterford, Clay M and Ellem, Kay A O
Journal: International journal of molecular sciences (2012): 2650-75
Lysosomal membrane permeabilization is an early event in Sigma-2 receptor ligand mediated cell death in pancreatic cancer.
Authors: Hornick, John R and Vangveravong, Suwanna and Spitzer, Dirk and Abate, Carmen and Berardi, Francesco and Goedegebuure, Peter and Mach, Robert H and Hawkins, William G
Journal: Journal of experimental & clinical cancer research : CR (2012): 41
Authors: Hornick, John R and Vangveravong, Suwanna and Spitzer, Dirk and Abate, Carmen and Berardi, Francesco and Goedegebuure, Peter and Mach, Robert H and Hawkins, William G
Journal: Journal of experimental & clinical cancer research : CR (2012): 41
Disassembly of the JIP1/JNK molecular scaffold by caspase-3-mediated cleavage of JIP1 during apoptosis.
Authors: Vaishnav, Mahesh and MacFarlane, Marion and Dickens, Martin
Journal: Experimental cell research (2011): 1028-39
Authors: Vaishnav, Mahesh and MacFarlane, Marion and Dickens, Martin
Journal: Experimental cell research (2011): 1028-39
Caspase 3 blocking avoids the expression of autoantigens triggered by apoptosis in neonatal Balb/c mice skin.
Authors: Ramírez-Sandoval, R and Vazquez-del-Mercado, M and Daneri-Navarro, A and Bollain-y-Goytia, J J and Avalos-Diaz, E and Herrera-Esparza, R
Journal: Reumatismo (2011): 29-37
Authors: Ramírez-Sandoval, R and Vazquez-del-Mercado, M and Daneri-Navarro, A and Bollain-y-Goytia, J J and Avalos-Diaz, E and Herrera-Esparza, R
Journal: Reumatismo (2011): 29-37
Role of VPO1, a newly identified heme-containing peroxidase, in ox-LDL induced endothelial cell apoptosis.
Authors: Bai, Yong-Ping and Hu, Chang-Ping and Yuan, Qiong and Peng, Jun and Shi, Rui-Zheng and Yang, Tian-Lun and Cao, Ze-Hong and Li, Yuan-Jian and Cheng, Guangjie and Zhang, Guo-Gang
Journal: Free radical biology & medicine (2011): 1492-500
Authors: Bai, Yong-Ping and Hu, Chang-Ping and Yuan, Qiong and Peng, Jun and Shi, Rui-Zheng and Yang, Tian-Lun and Cao, Ze-Hong and Li, Yuan-Jian and Cheng, Guangjie and Zhang, Guo-Gang
Journal: Free radical biology & medicine (2011): 1492-500
Proteasome activity profiling: a simple, robust and versatile method revealing subunit-selective inhibitors and cytoplasmic, defense-induced proteasome activities.
Authors: Gu, Christian and Kolodziejek, Izabella and Misas-Villamil, Johana and Shindo, Takayuki and Colby, Tom and Verdoes, Martijn and Richau, Kerstin H and Schmidt, Jürgen and Overkleeft, Hermen S and van der Hoorn, Renier A L
Journal: The Plant journal : for cell and molecular biology (2010): 160-70
Authors: Gu, Christian and Kolodziejek, Izabella and Misas-Villamil, Johana and Shindo, Takayuki and Colby, Tom and Verdoes, Martijn and Richau, Kerstin H and Schmidt, Jürgen and Overkleeft, Hermen S and van der Hoorn, Renier A L
Journal: The Plant journal : for cell and molecular biology (2010): 160-70
Evidence for caspase effects on release of cytochrome c and AIF in a model of ischemia in cortical neurons.
Authors: Singh, Maneesh H and Brooke, Sheila M and Zemlyak, Ilona and Sapolsky, Robert M
Journal: Neuroscience letters (2010): 179-83
Authors: Singh, Maneesh H and Brooke, Sheila M and Zemlyak, Ilona and Sapolsky, Robert M
Journal: Neuroscience letters (2010): 179-83
Application notes
FAQ
Do you offer any fluorimetric assays that measure caspase activation/activity in live cells using a flow cytometer?
What are common laser lines used in flow cytometry?
How can I tell if my cell sample is dying?
How does propidium iodide staining work?
What filters should I use for Apoptosis/Necrosis Assay Kit (Cat No. 22840)?
What are common laser lines used in flow cytometry?
How can I tell if my cell sample is dying?
How does propidium iodide staining work?
What filters should I use for Apoptosis/Necrosis Assay Kit (Cat No. 22840)?