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AAT Bioquest

Do the Golgi apparatus and endoplasmic reticulum work together?

Posted August 25, 2021


Answer

Yes, the Golgi apparatus and endoplasmic reticulum work together.

The Golgi apparatus or Golgi complex is located close to the rough endoplasmic reticulum (rough ER) allowing molecules to be easily transported between the two organelles.

Post translational modifications of the proteins occur inside the rough ER. The mature proteins are transported to the Golgi apparatus where they are sorted and packed into sealed droplets called vesicles to be transported to their eventual destination. Depending on the type of protein inside the vesicle, they may be dispatched within the cell to organelles called lysosomes, transported to the plasma membrane of the cell or secreted outside the cell into the extracellular environment.

Additional resources

Expression, sorting, and segregation of Golgi proteins during germ cell differentiation in the testis

Cell Navigator™ NBD Ceramide Golgi Staining Kit *Green Fluorescence*

Cell Navigator™ TMR Ceramide Golgi Staining Kit *Red Fluorescence*