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How do ionic detergents affect protein molecules?
Posted July 28, 2021
Plasma MembraneBioconjugation
Answer

Ionic detergents are capable of denaturing protein molecules irreversibly by breaking the intra- and intermolecular interactions. This alters the protein’s charge and structure and destroys their inherent biological activity.  

Additional resources
Quantification of Membrane Protein-Detergent Complex InteractionsPlasma MembraneDiOC3(3) iodide [3,3-Dipropyloxacarbocyanine iodide]

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