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What are inflammasome inhibitors?
Posted October 15, 2021

Answer

The aberrant activation of inflammasomes, the NLRP3 inflammasome in particular, has been linked to a wide range of inflammatory disorders. Considering the contributing role of inflammasomes in inflammatory disorders, inflammasome inhibitors are being rapidly developed in laboratories to curb inflammasome activation and potentially prevent a wide range of human disorders including metabolic, neurodegenerative, cardiovascular, and autoinflammatory conditions. Special focus is being paid to using inflammasome inhibitors in cancer prevention and treatment.