AAT Bioquest

What are second messengers?

Posted November 6, 2020


Second messengers are key intracellular molecules involved in many signal transduction pathways. These small, non-protein molecules and ions, relay extracellular signals received by cell surface receptors to target molecules within the cytosol. Common second messengers include calcium, cyclic nucleotides, inositol trisphosphate (IP3) and diacylglycerol (DAG).

Additional resources

Second Messengers

Intracellular Ions

Cal-520®, AM