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What does 7-AAD bind to?
Posted December 20, 2021
Cell Viability
Cell Cycle Assays
Cell Cytotoxicity
Physiological Probes
Answer
7-AAD
is a membrane impermeant intercalating dye. It binds to dsDNA by intercalating between base pairs in G-C-rich regions of DNA.
Additional resources
Dead cell discrimination with 7-amino-actinomycin D in combination with dual color immunofluorescence in single laser flow cytometry
Cell Meter™ Fluorimetric Fixed Cell Cycle Assay Kit *Red Fluorescence Optimized for Flow Cytometry*
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