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AAT Bioquest

What does the Golgi apparatus have to do with intracellular transport?

Posted April 2, 2021


Answer

The Golgi apparatus plays a key role in intracellular transport, which is the movement of vesicles and materials within the cell. It is responsible for modifying, packaging and transporting proteins and lipid molecules to different parts within the cell, such as delivering hydrolytic enzymes to lysosomes or proteins to be embedded in the plasma membrane. In intracellular transport, vesicles from the rough endoplasmic reticulum bring macromolecules to the Golgi for processing (e.g. protein glycosylation and lipid metabolism). After which they are sorted, repackaged back into transport vesicles and delivered to areas within the cell.

Additional resources

The Kiss-and-Run Model of Intra-Golgi Transport

Cell Navigator™ NBD Ceramide Golgi Staining Kit *Green Fluorescence*

Golgi Apparatus