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AAT Bioquest

How are lipids important in our body?

Posted February 22, 2024


Answer

Lipids have various important roles in the body. Triglycerides serve as a vital energy storage in the body. When the body requires energy, triglycerides can be broken down into fatty acids through a process called lipolysis. This fatty acid breakdown provides an efficient and concentrated source of energy, crucial for activities in different cellular functions. Steroid hormones play a key role in cellular communication and regulation. These hormones act as chemical messengers that bind to specific receptors on target cells, triggering a cascade of physiological responses. Examples include hormones like estrogen, testosterone, and cortisol. Phospholipids and cholesterol are essential components of biological membranes, forming the lipid bilayer that surrounds cells. Phospholipids function to create a selectively permeable barrier. Cholesterol, which is the most abundant steroid lipid found in the body, is essential for the functioning of every cell in the body. Bile salts synthesized from cholesterol in the liver aid in the digestion and absorption of dietary fats. Bile salts emulsify fat globules in the digestive system, breaking them into smaller droplets. This increased surface area facilitates the action of digestive enzymes, enabling the absorption of fatty acids and fat-soluble vitamins in the small intestine. Fatty acids serve as fundamental building blocks for the synthesis of complex lipids and play a crucial role in energy metabolism. During processes like beta-oxidation, fatty acids are broken down to generate ATP.  Lipids, particularly phospholipids, are vital components of the myelin sheath that surrounds nerve cells in the brain. Myelin functions to provide insulation and facilitates efficient nerve signal transmission.

Additional resources

What Are Lipids?

Cell Structures and Organelles

Cell Navigator® Fluorimetric Lipid Droplet Assay Kit *Red Fluorescence*