How are T-cells different from B-cells?

Question

Accepted Answer

Basis of differentiation

T-cells

B-cells

Definition

Are a type of lymphocyte that mediates appropriate immune responses against infected or malignant cells in the body by secreting lymphokines or by direct contact

Are a specific type of lymphocyte that transforms into two distinct groups – plasma cells and memory cells – on encountering a specific pathogen

Origin

Originate in the bone marrow and mature in the thymus

Originate and mature in the bone marrow.

Also known as

T lymphocytes

B lymphocytes

Surface antibodies

Lack surface antigens

Surface antigens are present

Membrane receptor for antigen

TCR (T-cell receptor)

BCR (B-cell receptor)

Recognition of Antigens

Can only recognize viral antigens on the outside of the infected cells

Can recognize antigens on the surface of the bacteria and viruses

Types of immunity

Are involved in the cell-mediated immunity (CMI)

Are involved in the humoral or antibody-mediated immunity (AMI)

Inhibitory effect

A specific type - Suppressor T cells - have an inhibitory effect on the immune system

Do not have any inhibitory effect on the immune system

Life span

Have longer lifespans

Have short lifespans

Secretion

Lymphokines

Antibodies

Types

3 types

Helper T cells
Cytotoxic T cells
Suppressor T cells

2 types

Plasma cells 
Memory cells

Movement to the infected site

Move to the site of infection

Do not move to the site of infection

Defend against

Pathogens such as viruses, protists, and fungi that enter the cells in the body

Bacteria and viruses in the bloodstream or lymph

Basis of differentiation	T-cells	B-cells
Definition	Are a type of lymphocyte that mediates appropriate immune responses against infected or malignant cells in the body by secreting lymphokines or by direct contact	Are a specific type of lymphocyte that transforms into two distinct groups – plasma cells and memory cells – on encountering a specific pathogen
Origin	Originate in the bone marrow and mature in the thymus	Originate and mature in the bone marrow.
Also known as	T lymphocytes	B lymphocytes
Surface antibodies	Lack surface antigens	Surface antigens are present
Membrane receptor for antigen	TCR (T-cell receptor)	BCR (B-cell receptor)
Recognition of Antigens	Can only recognize viral antigens on the outside of the infected cells	Can recognize antigens on the surface of the bacteria and viruses
Types of immunity	Are involved in the cell-mediated immunity (CMI)	Are involved in the humoral or antibody-mediated immunity (AMI)
Inhibitory effect	A specific type - Suppressor T cells - have an inhibitory effect on the immune system	Do not have any inhibitory effect on the immune system
Life span	Have longer lifespans	Have short lifespans
Secretion	Lymphokines	Antibodies
Types	3 types Helper T cells Cytotoxic T cells Suppressor T cells	2 types Plasma cells Memory cells
Movement to the infected site	Move to the site of infection	Do not move to the site of infection
Defend against	Pathogens such as viruses, protists, and fungi that enter the cells in the body	Bacteria and viruses in the bloodstream or lymph

Recognition of Antigens

Types of immunity

Inhibitory effect

Related questions