What are the advantages of covalent binding immobilization?

Covalent binding is an enzyme immobilization technique that involves connecting enzymes with support materials such as agarose, porous silica, or polyacrylamide, via strong, highly stable linkages. 

Advantages of Covalent Binding:

• Provides a strong binding force between an enzyme and a carrier
• Enhances stereospecificity of the enzymes so they are more stable
• No leaking enzymes so sufficient enzymes are recovered to be reused
• The process is not affected by ionic strength or pH
• Is a straightforward process
• Enhanced selectivity and potency, and prolonged duration of action offers multiple advantages for pharmacological applications