What are the advantages of covalent binding immobilization?

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Accepted Answer

Covalent binding is an enzyme immobilization technique that involves connecting enzymes with support materials such as agarose, porous silica, or polyacrylamide, via strong, highly stable linkages. 
Advantages of Covalent Binding:

Provides a strong binding force between an enzyme and a carrier
Enhances stereospecificity of the enzymes so they are more stable
No leaking enzymes so sufficient enzymes are recovered to be reused
The process is not affected by ionic strength or pH
Is a straightforward process
Enhanced selectivity and potency, and prolonged duration of action offers multiple advantages for pharmacological applications

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