What are the advantages of using a probe sonicator for chromatin fragmentation?

One key advantage is that ultrasonic probes focus ultrasonic energy to a specific area, usually at the probe's tip. This focused energy allows for precise treatment of samples. Compared to ultrasonic baths, probes concentrate more energy onto the sample, enhancing energy transfer. This focused transmission is beneficial for applications needing precise control, including cell disruption, botanical extraction and nanoparticle synthesis. Additionally it creates uniform shearing through cavitation, ensuring consistent results. Probe sonicators also offer flexibility and scalability, making them vital for various scientific and industrial uses.