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AAT Bioquest

What are the advantages of using multiple-sample sonicators for chromatin fragmentation?

Posted April 12, 2024


Answer

The main advantage is that multi-sample sonicators enable simultaneous sonication of multiple samples. Simultaneous sonication of multiple samples allows for higher throughput, enabling more efficient processing of large sample batches. Thus, sonication time is also reduced in the process. These devices also utilize either water bath sonication or focused ultrasonic technology, and possess an integrated cooling system for temperature control. Thus, these devices prevent overheating and sample damage. Multi-sample sonicators ensure consistent and reproducible sonication conditions across all samples, minimizing variability between experiments. Additionally, the risk for cross-contamination is eliminated.

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