What are the applications of cell sorting?
Posted May 24, 2023
Cell sorting is a process that isolates one or more target cell populations from a heterogeneous biological sample. The resulting homologous cell populations have significant applications in research and as therapeutics.
Applications of cell sorting include but are not limited to:
- Isolating WBC from tissue
- Isolating T cells, B cells, and other immune cells from peripheral blood
- Genetically modifying and expanding a specific target cell type for cell therapy research applications such as T cell therapy research or disease modeling
- Fusing enriched plasma cells with myeloma cells to create hybridomas
- Capturing CTCs or circulating tumor cells from blood
- Increasing the sensitivity of analytical techniques such as cell isolation for FISH analysis or cell isolation of HLA analysis
- Preparing a sample of blood separated from plasma
- Conducting molecular analysis of a single cell type, including epigenetic analysis and RNA expression
- Studying the in vitro effects of potential drug candidates on specific cell populations
- Separating pathogenic bacteria from food
- Using purified cells for adoptive cell transfer experiments directly in different animal models