Cell sorting is a process that isolates one or more target cell populations from a heterogeneous biological sample. The resulting homologous cell populations have significant applications in research and as therapeutics.
Applications of cell sorting include but are not limited to:
Isolating WBC from tissue
Isolating T cells, B cells, and other immune cells from peripheral blood
Genetically modifying and expanding a specific target cell type for cell therapy research applications such as T cell therapy research or disease modeling
Fusing enriched plasma cells with myeloma cells to create hybridomas
Capturing CTCs or circulating tumor cells from blood
Increasing the sensitivity of analytical techniques such as cell isolation for FISH analysis or cell isolation of HLA analysis
Preparing a sample of blood separated from plasma
Conducting molecular analysis of a single cell type, including epigenetic analysis and RNA expression
Studying the in vitro effects of potential drug candidates on specific cell populations
Separating pathogenic bacteria from food
Using purified cells for adoptive cell transfer experiments directly in different animal models