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AAT Bioquest

What is the significance of cell sorting?

Posted May 24, 2023


Answer

Cell sorting is a powerful yet gentle and efficient means of separating cells based on their unique intracellular or extracellular properties such as DNA, RNA, protein interactions, size, and surface protein expression. This technique is widely used to obtain homogenous cell populations from mixed cell samples, enabling researchers to study and understand the characteristics of a single cell population without the influence of other cells.

Cell sorting is used in a number of different applications including oncology and cancer research, drug discovery, immunology research, purifying engineered microbes, cloning purposes, disease modeling, and more. 

Additional resources

Fluorescence-activated Cell Sorting for Purification of Plasmacytoid Dendritic Cells from the Mouse Bone Marrow

Fluorescence Activated Cell Sorting (FACS)

ReadiUse™ CFSE [5-(and 6)-Carboxyfluorescein diacetate, succinimidyl ester] *CAS 150347-59-4*