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AAT Bioquest

What are the differences between physiological respiration and cellular respiration?

Posted November 6, 2023


Answer

Basis of differentiation

Physiological respiration

Cellular respiration

Definition

Is a physiological process which involves inhaling and exhaling air 

Is the process of producing energy from glucose, when oxygen is present 

Occurrence

Breathing occurs between the external environment and the body (in the lungs, nose, and diaphragm)

Cellular respiration occurs in cells and organelles (mitochondria)

Stages

Inhalation and exhalation

Glycolysis, TCA cycle, oxidative phosphorylation, and electron transport chain

Involvement of enzymes

Enzymes not required for breathing

Requires the use of enzymes

Voluntary or involuntary

Breathing can either be voluntary or involuntary

Cellular respiration is always involuntary

Energy production

Energy is not produced as a byproduct of breathing

Cellular respiration produces energy and waste products

Energy use

Breathing involves passive (expiration) and active processes (inspiration)

Cellular respiration is solely an active process 

Type

Breathing is a physical process

Cellular respiration is a biochemical process

Function

The primary functions of breathing are gas exchange (exhale carbon dioxide) and ventilation

The primary functions of cellular respiration are gas exchange and break down of nutrients to form carbon dioxide, water, and energy

Additional resources

Difference between breathing and respiration

Cellular Processes

Cell Signaling

PhosphoWorks™ Fluorimetric ATP Assay Kit