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AAT Bioquest

What are the differences between ribonucleotide and deoxyribonucleotide?

Posted April 19, 2024


Answer

Basis of differentiation

RIbonucleotide

Deoxynucleotide

Definition

Is a nucleotide which contains ribose and occurs as a component of RNA

Is a nucleotide which contains deoxyribose and occurs as a component of DNA

Presence of oxygen

Has a hydroxyl group (OH) on the 2' carbon

Lacks a hydroxyl group on the 2' carbon

Stability

Less stable due to the presence of the 2'-OH

More stable due to absence of the 2'-OH group

Splicing

Allows splicing

Does not allow splicing

Base pairs in DNA/RNA

Adenine, guanine, uracil, and cytosine

Adenine, guanine, thymine, cytosine

Additional resources

Difference Between Ribonucleotide and Deoxyribonucleotide

DNA and RNA Quantitation

Helixyte™ Green ssDNA reagent

DNA Concentration Calculator