DBCO-Cy3 | AAT Bioquest

DBCO-Cy3

This azadibenzocyclooctyne-cyanine dye derivative is a versatile labeling reagent for detection of azide containing molecules or compounds. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide-functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. AAT Bioquest offer a broad range of dye azide compounds (such as coumarin azides, fluorescein azides, rhodamine azides and cyanine azides) for click reactions.

Catalog	Size	Price	Quantity
920	1 mg	Price

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of DBCO-Cy3 to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	84.348 µL	421.742 µL	843.483 µL	4.217 mL	8.435 mL
5 mM	16.87 µL	84.348 µL	168.697 µL	843.483 µL	1.687 mL
10 mM	8.435 µL	42.174 µL	84.348 µL	421.742 µL	843.483 µL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	1185.56 g/mol	=	mL	x	mM	=	mmol

Citations

View all 2 citations: Citation Explorer

Imaging of antitubercular dimeric boronic acids at the mycobacterial cell surface by click-probe capture

Authors:

Guy, Collette S and Tom{\'a}s, Ruben MF and Tang, Qiao and Gibson, Matthew I and Fullam, Elizabeth

Journal:

Chemical Communications (2022): 9361--9364

Site-specific chemical conjugation of human Fas ligand extracellular domain using trans-cyclooctene--methyltetrazine reactions

Authors:

Muraki, Michiro and Hirota, Kiyonori

Journal:

BMC biotechnology (2017): 56

References

View all 49 references: Citation Explorer

Beyond click chemistry - supramolecular interactions of 1,2,3-triazoles

Authors:

Schulze B, Schubert US.

Journal:

Chem Soc Rev (2014): 2522

Calixarene-based chemosensors by means of click chemistry

Authors:

Song M, Sun Z, Han C, Tian D, Li H, Kim JS.

Journal:

Chem Asian J (2014): 2344

Use of click-chemistry in the development of peptidomimetic enzyme inhibitors

Authors:

Fabbrizzi P, Menchi G, Guarna A, Trabocchi A.

Journal:

Curr Med Chem (2014): 1467

Applications of copper-catalyzed click chemistry in activity-based protein profiling

Authors:

Martell J, Weerapana E.

Journal:

Molecules (2014): 1378

'Click chemistry' for diagnosis: a patent review on exploitation of its emerging trends

Authors:

M, undefined and hare A, Banerjee P, Bhutkar S, Hirwani R.

Journal:

Expert Opin Ther Pat (2014): 1287

Physical properties

Molecular weight	1185.56
Solvent	DMSO

Spectral properties

Correction factor (260 nm)	0.07
Correction factor (280 nm)	0.073
Extinction coefficient (cm ^-1 M ^-1)	150000 ¹
Excitation (nm)	555
Emission (nm)	569
Quantum yield	0.15 ¹

Storage, safety and handling

Certificate of Origin	Download PDF
H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501
CAS	1782950-79-1

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Page updated on September 27, 2025